Behavior of Exogenously-introduced DNAs in Early Embryos of Xenopus laevis
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概要
- 論文の詳細を見る
Studies of the behavior of circular and linearized DNAs, injected into fertilized eggs of Xenopus laevis, have been reviewed. The review consists mainly of three parts : Formation of nucleus-like structures in the cytoplasm of the DNA-injected eggs, preservation and replication of injected DNAs within embryos, and expression of injected DNAs in the course of early embryonic development. The last part of the review is concerned with the control of the expression of circular and linearized DNAs, and will be discussed in some details, particularly in relation to the timing of the expression in early embryogenesis. Previously, it has been reported that DNAs injected into fertilized Xenopus eggs are activated first at the 12th cleavage (the midblastula stage) along with the changes which are collectively called midblastula transition (MBT). However, this review will focus on our own data, in which it was shown that the nature of the promoter, and not the changes associated with the MBT, determines the timing of the expression of injected DNAs.
- 社団法人日本動物学会の論文
- 1993-04-15
著者
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SHIOKAWA Koichiro
Laboratory for Molecular Embryology, Zoological Institute, Faculty of Science, University of Tokyo
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Asano Misaki
Laboratory Of Molecular Embryology Zoological Institute Faculty Of Science University Of Tokyo
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Shiokawa Koichiro
Laboratory Of Molecular Embryology Zoological Institute Faculty Of Science University Of Tokyo
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