Effects of Androgen on Mouse Seminal Vesicle Epithelial Cells in Serum-Free Culture : Endocrinology
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概要
- 論文の詳細を見る
ABSTRACT-The effects of androgen were studied on mouse seminal vesicle epithelial cells in serum-free primary collagen gel culture . Androgen had no growth-promoting effect on the epithelial cells when tested in "optimal" serum-free medium. However, androgen stimulated growth in serum-free medium supplemented with epidermal growth factor and insulin at lower concentrations ("suboptimal" medium). Both testosterone and 5a-dihydrotestosterone (DHT) were effective, but progesterone and estrogens had no significant effect on growth. The effect of DHT (10^<-8>M) on androgen receptor content was studied in epithelial cells grown in both the optimal and the suboptimal serum-free media. The hormone reduced the number of receptors in the cytosol and increased the number in the nucleus in both media.
- 社団法人日本動物学会の論文
- 1990-08-15
著者
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BERN Howard
Department of Integrative Biology, Cancer Research Laboratory and Bodega Marine Laboratory, Universi
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Bern Howard
Department Of Integrative Biology And Cancer Research Laboratory University Of Californi
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Mills K
Univ. California California Usa
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Tomooka Y
Department Of Biologocal Science & Tecnology Tokyo University Of Science
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TOMOOKA YASUHIRO
Developmental Endocrinology and Pharmacology Section, Laboratory of Reproductive and Developmental T
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EDERY MARC
Department of Integrative Biology and Cancer Research Laboratory, University of Californi
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MILLS KAREN
Department of Integrative Biology and Cancer Research Laboratory, University of Californi
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MCLACHLAN JOHN
Developmental Endocrinology and Pharmacology Section, Laboratory of Reproductive and Developmental T
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Edery Marc
Department Of Integrative Biology And Cancer Research Laboratory University Of Californi:unite D&apo
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Mills Karen
Department Of Integrative Biology And Cancer Research Laboratory University Of California(present Ad
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Mclachlan John
Developmental Endocrinology And Pharmacology Section Laboratory Of Reproductive And Developmental To
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