Superoxide Production by the Haemocytes of the Freshwater Snail, Biomphalaria glabrata, Stimulated by Miracidia of Schistosoma mansoni : COMMUNICATION : Immunology

概要

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The production of superoxide (O_2^-) by the haemocytes of Biomphalaria glabrata, an intermediate host of Schistosoma ,nansoni, was demonstrated by nitroblue tetrazolium (NBT) test. Intact, 4,000 R irradiated and formalin-fixed miracidia (snail-infective larvae) of S. mansoni were used as the stimuli. NBT-reduction was observed in the haemocytes incubated with 4,000 R irradiated or formalin-fixed miracidia, whereas only little effect was shown by intact ones. The reduction was inhibited by superoxide dismutase. The results suggest that self/non-self recognition by the haemocytes is involved in the O_2^- production.
社団法人日本動物学会の論文
1989-10-15