Gonad Response to γ-Aminobutyric Acid in the Sea Urchin : Physiology

概要

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In the sea urchin, Strongylocentrotus intermedius, gonad response to γ-aminobutyric acid (GABA) was examined by indirect measurements of gonad contraction. (1) Mechanical response was noted to increase with gonad growth. Young growing gonads showed small response but for maturing, ripe and post-spawning specimens, the response was large. (2) Two different GABA responses on the part of maturing, ripe and post-spawning gonads, and young and growing gonads were thus in evidence. In the former, there were both phasic and rhythmical contractions but in the latter, only phasic contraction. (3) GABA response was also noted to vary according to sex. In the female, the appearance of rhythm was high, but low in the male. (4) The duration of GABA response was about 20 min in maturing and ripe gonads. (5) The threshold concentration of GABA response was 0.01mM. The 50% effective and maximal doses were 0.1mM and 10mM, respectively. (6) The sites of action of GABA injected at a concentration of 10mM were examined. GABA acted directly on the gonads. The generator inducing phasic and rhythmical contraction is discussed.
社団法人日本動物学会の論文
1987-06-15