Modeling and Simulation of Fission Yeast Cell Cycle on Hybrid Functional Petri Net(Hybrid Systems)(<Special Section>Concurrent Systems and Hybrid Systems)

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概要

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• Through many researches on modeling and analyzing biological pathways, Petri net has recognized as a promising method for representing biological pathways. Recently, Matsuno et al. (2003) introduced hybrid functional Petri net (HFPN) for giving more intuitive and natural biological pathway modeling method than existing Petri nets. They also developed Genomic Object Net (GON) which employs the HFPN as a basic architecture. Many kinds of biological pathways have been modeled with the HFPN and simulated by the GON. This paper gives a new HFPN model of "cell cycle of fission yeast" with giving six basic HFPN components of typical biological reactions, and demonstrating the method how biological pathways can be modeled with these HFPN components. Simulation results by GON suggest a new hypothesis which will help biologist for performing further experiments.

• 社団法人電子情報通信学会の論文
• 2004-11-01

著者

• MIYANO Satoru

  Human Genome Center, The Institute of Medical Science, University of Tokyo

• Miyano Satoru

  Human Genome Center Institute Of Medical Science The University Of Tokyo

• Matsuno Hiroshi

  Oshima National College Of Maritime Technology

• Matsui Mika

  Graduate School Of Science And Engineering Yamaguchi University

• FUJITA Sachie

  Showa Pharmaceutical University

• Fujita Sachie

  Graduate School Of Science And Engineering Yamaguchi University

• Matsui M

  Graduate School Of Science And Engineering Yamaguchi University

• MATSUNO Hiroshi

  Faculty of Science, Yamaguchi University

• Miyano S

  Human Genome Center Institute Of Medical Science The University Of Tokyo

• Matsuno Hiroshi

  Faculty Of Science Yamaguchi University

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