潰瘍性大腸炎に対する遠心分離法による白血球除去療法(<特集>白血球系細胞除去療法の最近の展開)

概要

論文の詳細を見る
In Japan, leukocyte apheresis is now considered to be one of the standard treatments for UC patients with refractory disease to avoid surgery. Therapeutic efficacy of leukocyte apheresis using the centrifugal cell separator, was proven by a multicenter clinical trial. As a result, five or six consecutive leukocyte aphereses, which were undergone weekly, improved both symptoms and endoscopic findings in approximately 73% of patients with UC. The data obtained from this trial was almost identical to those from the clinical trials using the leukocyte-absorbing column, or leukocyte removal filter devices. These results suggest that the removal of activated leukocyte fractions from peripheral blood inhibits the further progression of colonic inflammation.
日本アフェレシス学会の論文
2005-05-31