PRODUCTION AND LOCALIZATION OF HUMAN PROLACTIN IN HUMAN CHORIONIC TISSUE AND DECIDUA
スポンサーリンク
概要
- 論文の詳細を見る
Prolactin, a peptide hormone in pituitary glands, shows a remarkable increase in amount in both plasma and amniotic fluid during pregnancy. In the plasma of the pregnant female, there is a rectilineal relationship between the increase of a measurable amount of prolactin and the progress of gestation. The highest level of amniotic prolactin is observed between the 15th and the 17th week of pregnancy. The production site as well as the function of prolactin during pregnancy have been disputed. In the present paper, the authors describe the production and localization of prolactin materializing tissues of human placenta and decidua in early pregnancy (from the 7th to the 9th week after last menstruation) obtained by either hysterectomy or curette. Immunohistological investigations revealed that syncytial trophoblast is a production site of prolactin. Prolactin was recognized in decidua tissue which does not produce but only deposits the prolactin. By a method of double staining, the production and localization of either beta-subunit of human chorionic gonadotropin (hCG-β) or human placental lactogen (hPL) were manifestatively differentiated from that of prolactin in syncytial trophoblast.
- 日本組織細胞化学会の論文
著者
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YOSHIDA Yoshinobu
Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
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Yoshida Yoshinobu
Departments Of Obstetrics And Gynecology Shiga University Of Medical Science
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KASAI Kanji
Department of Biofunctional Science, Faculty of Agriculture and Life Science, Hirosaki University
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Kasai Kanji
Department Of Biofunctional Science Faculty Of Agriculture And Life Science Hirosaki University
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AOCHI HIDEKI
Department of Obstetrics and Gynecology, Shiga University of Medical Science
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Aochi Hideki
Department Of Obstetrics And Gynecology Shiga University Of Medical Science
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KASAI KANJI
Department of Obstetrics and Gynecology, Shiga University of Medical Science
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YOSHIDA YOSHINOBU
Departments of Obstetrics and Gynecology, Shiga University of Medical Science
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KASAI KANJI
Departments of Obstetrics and Gynecology, Shiga University of Medical Science
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