A STUDY OF POTASSIUM PERMANGANATE FIXATION FOR ELECTRON MICROSCOPIC DETECTION OF SMALL GRANULAR VESICLES IN THE SYMPATHETIC NERVOUS SYSTEM
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概要
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A 3% solution of potassium permanganate is effective at acid pH as a fixative for the small noradrenaline-containing granular vesicles of the symapthetic nervous system. The observed high electron density of the central granules in the vesicles is probably due to precipitated MnO_2 which is reduced KMnO_4, in a coupled oxidation of noradrenaline to noradrenochrome. A 3% solution of KMnO_4 in dichromate buffer (pH 6.0) is particularly suitable for the fixation of the vesicles. This may be due to the additional precipitation of a chromic compound reduced from the dichromate.
- 日本組織細胞化学会の論文
著者
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OCHI JUNZO
Department of Anatomy, Kyoto Prefectural University of Medicine
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Ochi Junzo
Department Of Anatomy (director: Prof. Y. Sano) Kyoto Prefectural University Of Medicine
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