膀胱腫瘍の保存的治療後の再発について

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A clinical study with periodic check-ups of 84 patients who had TUR, TUC or partial cystectomy for cure or control of bladder tumor and in whom there were one or more recurrences is reported. The results were as follows: 1) Primary recurrences were found in 49 out of the 84 cases (58%). The number of repeated recurrences was one to 8, averaging 1.9. 2) There were two peaks of incidence of recurrence, within 6 months and between one and three years after the treatment. The time of recurrence after TUR and TUC is rather later than that after partial cystectomy. 3) The recurrence was most frequently found solitary and at the same place as the original tumor. 4) The incidence of recurrence was generally high in cases with multiple tumor and tumor with atypical histology. 5) The frequency of recurrences in other part of the bladder was higher in multiple recurrent cases than in single recurrent cases. 6) Histological examination of the specimen obtained in partial cystectomy demonstrated proliferative changes with epithelial hyperplasia close to the tumor. The incidence of such changes developing 5 mm or more from the tumor margin was 7 1 and 23 per cent in recurrent and non-recurrent cases, respectively. 7) There were no recurrence in 3 cases who had bladder irrigation with anticancer drug after TUR 8) There were 4 cases with total cystectomy after repeated conservative treatment. From the results above mentioned it was stressed that bladder irrigation of anticancer drug after TUR and TUC and sufficient resection of the bladder wall in partial cystectomy is of utmost importance.
社団法人日本泌尿器科学会の論文

膀胱腫瘍の保存的治療後の再発について

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