後部尿道の形態および機能に関する実験的研究 : 雄性犬尿道の筋構築と Urethral Pressure Profile について

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Macroscopic, microscopic observation and dissection were carried out on the urethral musculature running from the internal meatus to the posterior urethra of the male dog. Urethral pressure profile was also investigated with the same materials. Moreover, various drugs (adrenergic, cholinergic and muscle relaxant) were administrated, and those effects on the profile were investigated. The experimental results contained the following urethral pressure was divided by two main muscles, namely, the one was the smooth muscle, taking part in the extension of the detrusor muscle and drawing the flat profile in the prostatic urethra, and the other was the striated muscle which formed UPmax from the distal part of the prostate to the region attached to the pelvic floor muscles. The tubular structure of the striated muscle played an important role of the sphincteric action. According to the results of the urethral pressure profile with the sympathetic drugs administration, both the α-receptor and the β-receptor were confirmed to respond to the smooth muscle and the striated muscle of the urethra. Moreover, the α-receptor response was seen predominantly in the male canine urethra as reported by other investigators. The effect of the parasympathetic drugs administration on the urethral pressure profile was both stimulation and blockade in the prostatic urethra, but there was no response in the striated muscle of the urethra. The striated muscle of the urethra, which differed from ordinary skeletal muscle in its character, assumed the special attitude of the striated muscle dominated by the sympathetic nerve.
社団法人日本泌尿器科学会の論文

後部尿道の形態および機能に関する実験的研究 : 雄性犬尿道の筋構築と Urethral Pressure Profile について

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