左腎静脈結紮の実験的研究

概要

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The renal vein is one of the most important veins in the body. Therefore, its obstruction causes various diseases, which may be fatal at times. On the other hand, it is said that the left kidney can retain its renal function owing to its being rich in collateral circulation. However, no adequate studies have been carried out concerning this subject since a few number of investigations have been undertaken. In this study in 31 mongrel dogs, the left renal veins of animals were ligated centrad to the confluence of the testicular vein in order to determine the course, global renal functions, fluctuations of the blood enzymes levels, renal histological changes, process of collateral vascularization and the left renal functions one to four weeks after the removal of the right (namely the opposite side) kidney. 1. Out of the 31 dogs with the left renal vein ligated, 28 dogs (93.5%) survived more than one to four weeks. This fact indicates that the ligature of the left renal vein of dogs is not always followed by fatal hemorrhage in the perirenal area or high mortality rate but can be tolerated adequately in general. 2. In 5 dogs in which determinations of the serum creatinine levels were carried out for 2 weeks after the ligature of the left renal vein, it was found that all the fluctuations remained within the normal limit.
社団法人日本泌尿器科学会の論文