ヒト泌尿生殖器系悪性腫瘍の異種移植に関する研究 : 第II報ヌードマウス可移植性ヒト膀胱癌に対する治療実験ならびにハムスターへの移植実験

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For their characteristic of exhibiting no rejection of allogeneic tissue due to congenitally absent T-cell function, the nude mice reported by Issacson for the first time in 1962 have been calling for attention in the discipline of cancer research in recent years. It has been demonstrated by some investigators that the nude mice, when applied to experiments of cancer response to various treatments, including carcinostatics, have proved an experimental system considerably close to an ideal one available at present, without the drawbacks of the other systems used for the same purpose. Since 1977, the author has been successfully subtransplanting various human urogenital malignant neoplasms in the nude mice, and recently performed experimental treatments of a human bladder cancer transplantable to the nude mice (Bl-4).
社団法人日本泌尿器科学会の論文
1979-08-20

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