上部尿路機能に関する研究 : 第10報 手術侵襲時における尿管壁内微小循環
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概要
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The purpose of this study was to determine if ureteral microcirculation is influenced by a ureterah surgery. Twenty dogs weighing 11 to 24 kg were anesthetized with Thiopental and the mid-ureter was exteriorized transperitoneally. Surgery was done at different sites of the ureter : Exp. II, transection at the ureterovesical junction (U.V.J.); Exp. II, transection at ureteropelvic junction (U.P.J.); Exp. III, transections at both the U.P.J. and U.V.J.; and Exp. IV, transections at both the U.P.J, and U.V.J., combined with detachment of the whole ureter from its supporting tissues. Ureteral intramural PO_2, an index of ureteral blood flow, was continuously monitored by using the Yagi's polarographic oxygen electrode of an enameled copper wire 300 μ in diameter implanted in the ureteral intramural tissues. Changes in the polarographic amplitudes following surgery were expressed as 100 of the preoperative level. The results obtained were as follows : 1. In all cases the ureteral intramural PO_2 was significantly decreased in the ureters receiving a surgical stress. The mean values of the ureteral intramural PO_2 Were 80±18, 79±24, and 72±22 in the Exp. I, II and III, respectively. The most striking reduction of the ureteral intramural PO_2 (42±27) was observed in the Exp. IV, in which transections were made at the U.P.J. and U.V.J., combined with detachment of the whole ureter from its supporting tissues.
- 社団法人日本泌尿器科学会の論文
- 1978-07-15