上部尿路機能に関する研究 : 第9報 利尿状態時における尿管の尿搬送能および尿管壁内微小循環
スポンサーリンク
概要
- 論文の詳細を見る
The studies reported here were undertaken to relate ureteral blood flow to ureteral peristalsis activity during diuresis. Twenty-eight dogs weighing 13 to 23 kg were anesthetized with Thiopental and the ureter was exteriorized transperitonbally. Ureteral peristalsis was continuously recorded by electromyography and intraureteral pressure measurement. Diuresis was induced by an intravenous administration of Furosemide (1 mg/kg). Urine was collected every 5 min. through a catheter (2 mm in outer diameter : 1 mm in inner diameter) placed in the lower ureter, and the ureteral stroke volume was estimated. Ureteral intramural PO_2, an index of ureteral blood flow, was continuously measured by using Yagi's polarographic oxygen electrode of an enameled copper wire 300 μ in diameter implanted in the ureteral intramural tissues. Changes in the polarographic amplitudes during diuresis were expressed as 100 of the prediuretic level. The results obtained were as follows : 1. The mean increment of the ureteral intramural PO_2 during 100% oxygen breathing was 197 (115-660). Thus, the Yagi's polarographic PO_2 measurement was proved to be a useful tool for monitoring ureteral intramural PO_2 in situ. 2. The increase in ureteral intramural PO_2 during oxygen breathing was accompanied by no change in ureteral peristalsis activity. 3. Three type of ureteral response to diuresis were observed : 1) Type I, frequent and persistent peristalsis, 2) Type II, frequent, but short-lived peristalsis, and 3) Type III, no remarkable change in peristalsis. Regardless of the types of response the ureteral stroke volume was increased. The ureteral stroke volume was lowest in the first type and largest in the second type.
- 社団法人日本泌尿器科学会の論文
- 1978-07-15