歯肉切除創の治癒経過にともなう神経線維分布の消長に関する研究
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概要
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Gingivectomy was performed experimentally in adult rhesus monkeys and patho-histological and neurohistological observations were made of the healing process of the wounds for six weeks from the second day after operation. The results were as follows : 1. Regeneration of the epithelium of the gingivectomy wounds began on the second day after operation and the surface coverage of the wounds was complete on the tenth day. 2. Proliferation of young granulation tissue in the lamina propria of the gingiva began on the third day. Fibration followed and the direction and arrangement of fibers became regular on the 28th day, findings similar to the control's. 3. Bone resorption at the alveloar process was observed in about a half of the cases between the first and fourth week and in two out of six cases in the sixth week. Addition of new bones began on the tenth day and increased thereafter, and the similar findings were observed in four out of six cases in the sixth week. 4. Findings of degeneration such as swelling, lacerations, hypochromatosis, and granular decomposition were observed as early as on the second day around the central cut-surface of the nerve fibers severed in gingivectomy. 5. The degenerative findings around the cut-surface gradually advanced toward the central side and were the most significant on the fifth day. The degeneration of nerve fibers extended to the mucobuccal fold in the alveolar mucous membrane and to the apical region in the periodontal membrane. 6. Regeneration of nerve fibers began in the first week and formation of Bungner's bands was observed in the periodontal membrane from the dental neck to a half of the root and under the attached gingival mucous membrane. 7. Many minute regenerated nerve fibers were seen in the margin of granulation tissue under the new free gingival mucous membrane on the tenth day. Regenrated knob-like nerve endings were seen under the new attached gingival mucous membrane. 8. The findings in the periodontal membrane at the apical region in the second week were about the same as for the control. The amount of distribution however was slightly increased. 9. Many regenerated nerve fibers and free nerve endings were seen under what is called new free gingival mucous membrane of the external marginal epithelium and inner marginal epithelium, and their distribution was about the same as for the control. 10. The nerve fibers under the periodontal membrane and alveolar mucous membrane were still minute in the fourth week and the amount of distribution increased slightly compared with that for the control. The findings in the sixth week were about the same as for the control.
- 九州歯科学会の論文
- 1980-11-25
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