同一正常非妊婦における腎機能因子の最大變動範圍の設定とその意義について

概要

論文の詳細を見る
The reaction of various agents on the kidney is being studied widely today by using renal clearance tests and quite a number of new findings are being reported these days. At present we are examining how the medicines most widely used against pregnancy toxemia today work on the kidney.As a preliminary step, we have tried to ascertain how far renal function factors vary with the same individual subject. And with the purpose of establiching standards for future experiments, we have measured the renal function factors by using PAH and Thiosulfate for two hours straight on 19 different cases using the same normal non-pregnant woman and tried to find the limits where we are to renounce the findings.As a result we discovered that in conducting renal clearance tests by performing loading tests with various agents, we can say that the agents have significant effects on the kidney only when various clearance values obtained by such tests are fluctuating above the limits where they are to be renounced. [table] When the clearance values obtained after one hour fluctuate above the above-mentioned percentages as compared with the first clearance values, they are of significance.
社団法人日本循環器学会の論文
1958-03-20