心筋代謝に関する研究 : (II)実験的冠不全時の心筋電解質代謝におよぼすADENOSINE TRIPHOSPHATEの影響
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As a means to reveal the influence of ATP on the heart, ATP was injected intravenously to dogs with experimental coronary insufficiency, and the change of myocardial electrolyte metabolism was studied. Immediately or three minutes after the injection of ATP (20mg) the difference of Mg level between artery and vein showed an increase at first, that of K a remarkable increase, secondly, and then they rapidly decreased temporaly, which, however followed by an increase in various extent. Administration of ATP with cocarboxylase or α-lipoic acid showed a marked increase of the defference of K- and Mg-level in artery and vein within three minutes and 7-21 minutes after the injection. With regards to those of Na- and Ca-level, a definite trend were not found though in some cases it showed a reversal tendency to those of K- and Mg-level.
- 日本ビタミン学会の論文
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