パントテン酸要求性大腸菌変異株の研究 : (II)β-アラニン要求株の性状とカルノシンの栄養活性

概要

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In the synthetic medium of Davis-Mingioli, the mutant strain #79,derived from E.coli O-20,responded to a much smaller amount of pantothenic acid than to the amount of β-alanine. The growth by β-alanine was inhibited by casein hydrolysate or certain amino acids. The growth activity of L-carnosine for the mutant was comparable to that of pantothenic acid. Water extract of beef supported the growth of the mutant even when diluted to 1 : 40,000. The activity was also found in the chicken extract. The experimental evidence is presented to show that the factor in meat extract responsible for the mutant may be carnosine, anserine or an analogous substance.
日本ビタミン学会の論文