スルフォンアミドで発育抑制した鳥型結核菌に蓄積するジアゾ反応陽性物質について : (II)ビタミンB_2生合成におよぼす影響

概要

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4-Amino-5-imidazole carboxamide ribotide and 4-amino-5-imidazole carboxamide riboside derivative (tentatively named as D_1 substance), which had been separated from the cells of Mycobacterium avium partially inhibited by sulfathiazole, were studied on the influence on the biosynthesis of riboflavin. They were found to promote the flavin biosynthesis in vitro in the extract of acetone-dried normal cells of Mycobacterium avium. Their promoting actions were supported by coexistence of ATP and boiled extract of normal cells, and were degradedby cotransformylase.
日本ビタミン学会の論文