抗生物質のビタミンA代謝に及ぼす影響 : (V)ホモスルファミン投与がシロネズミ肝, 小腸, 血清中ビタミンA量に及ぼす影響ならびにビタミンA負荷実験

概要

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The vitamin A contents of liver, small intestine and blood serum were determined by the fluorometric method after one, two, three and four week feeding on 200 mg per kg of body weight of homosulfamine containing diet. No significant changes as compared with control groups were found in the vitamin A contents. The vitamin A contents of liver, small intestine and blood serum were determined one, three, six and twenty four hours after an intravenous injection of 1 mg of vitamin A to the rats fed four weeks on homosulfamine containing diet. The results showed that after vitamin A administration the vitamin content of liver slowly increased and that of blood serum slowly decreased while the vitamin A in small intestine underwent insignificant changes, as compared with the control groups. It could be postulated that the change of vitamin A in liver and blood serum after loading of the vitamin was due to liver dysfunctions by homosulfamine administration.
日本ビタミン学会の論文
1959-00-00