抗生物質投与時のビタミンB_1代謝に関する組織化学的研究 : (II)オーレオマイシン少量投与シロネズミの臓器組織のビタミンB_1分布

概要

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Similar studies as previous report were conducted when 20 mg per kg per day of Aureomycin was administered. A remarkable increase of thiamine in the organs, especially in the liver was observed. The growth of the rat administered with Aureomycin was promoted than that of the control. In the thiamine loading, the increases of thiamine were more evident in liver, kidney and small intestine. These results indicate that the increase of thiamine in the organs was due not only to the stimulation of thiamine synthesis by intestinal bacteria but also to the promotion of phosphorylation of thiamine in the liver by the administration of Aureomycin in small quantity.
日本ビタミン学会の論文