ビタミンB_1関連化合物の微生物活性 : (II)PHOSPHATE, ACYLおよびその他の型のビタミンB_1誘導体のLactobacillus fermenti活性

概要

論文の詳細を見る
In a similar way to the previous work concerning the effects of the disulfide derivatives of thiamine for the growth of L.fermenti, the activities of the phosphoric, acyl and other derivatives of thiamine were examined. The phosphoric esters, i.e. thiamine mono- and diphosphates were more effective than thiamine hydrochloride, while the acyl derivatives, i.e. O-acetyl or benzoyl thiamine and O, S-diacetyl or dibenzoyl thiamine showed no apparent effects on the growth of the microorganism. S-Benzoyl thiamine monophosphate exerted an activity, but it was labile and variable under certain conditions of dissolution or heat treatment. Thio-, oxy-, dihydro-, or anhydro-thiamine and thiochrome showed no recognizable activity, while the effect of cyano- or ethyl-thiamine was similar to that of thiamine hydrochloride.
日本ビタミン学会の論文