生体における遊離型および結合型ビタミンAに関する研究 : (II)血清蛋白画分中の遊離型および結合型ビタミンAについて

概要

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In various diseases, especially in kidney disorders, which exert the effect on protein of the p1asma, abnormal changes of the free and esterified vitamin A contents are often observed. Therefore, the amounts of free and esterified vitamin A in the fractions of protein of the human and rabbit plasma were determined by means of the chemical and Tiselius' electrophoretical method. By the chemical analysis, both types of the vitamin were detected mainly in the globulin fraction. Although a similar result was obtained by means of the Tiselius' method, the existence of esterified vitamin A in the alubumin fraction was also proved. However, the vitamin seemed to be contained in the globulin fraction in view of the principle of electrophoresis.
日本ビタミン学会の論文