天然ビタミンA油および合成ビタミンA油の比較 : (II)生体内の組織化学的分布について

概要

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Histochemically active glycerol dichlorohydrine was used and it was observed by a fluorescence-microscope. (1) The intestinal absorption was more ready with tunny liver oil and distilled cod liver oil than with synthetic vitamin A oil, shark liver- and cod liver oil. (2) In cells, some granules of vitamin A were found together, and the others not together, with lipoid. In the former the granules were fine in rats adminstered with natural vitamin A oil, and coarse and various in size in rats with synthetic oil. In the latter, all the granules were minute in size. They were less in number in rats with synthetic vitamin A oil than in those with natural oil. (3) In the adrenal cortex, vitamin A was found in a little larger amount in rats administered with natural vitamin A oil than those with the synthetic one, but no such difference could be seen in the retina. (4) Fat is oxidized and destroyed in the lung. The vegetative oils are more difficult to be utilized than the animal fats. (5) The discharge of vitamin A by the kidney is somewhat more rapid with natural vitamin A oil than with synthetic one.
日本ビタミン学会の論文