網膜のビタミンAの組織化学的研究 : (II)シロネズミのビタミンA欠乏症における網膜の視紅再生とビタミンA消長の経時的観察

概要

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Active glycerol dichlorohydrine was used and observations were made with a fluorescence microscope. (1) In the retina, especially in the pigment epithelium, vitamin A appeared 3 hours after its administration, but the quantity was not always proportional to the administered doses, no positive result was detected by the glycerol dichlorohydrine method. (2) The amount of vitamin A required for regeneration of rhodopsin, is very small, but vitamin A plays an important role in the maitenance of function recovery of rhodopsin in the pigment epithelia and visual cells. (3) The delay of rhodopsin regeneration of vitamin A-deficient rats is due to functional insufficiency of the pigment erithelia and visual cells, which recover in a few days after administration of vitamin A, rather than to the shortage of vitamin A for direct use in the process of rhodopsin regeneration.
日本ビタミン学会の論文