葉酸欠乏症シロネズミのSalmonella enteritidis経口感染

概要

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Salmonella enteritidis S 64 was orally administered to normal and folic acid deficient rats. No death was recognized in the both groups in a low dose (4×10^8 cells) of the bacillus, while the animals deficient in folic acid died 10 to 12 days after the ingestion of the bacillus as much as 1×10^9 cells. In the dead animals, the bacillus was detected in the heart blood, the liver, the spleen and the intestinal tracts, but not in those of the normal animals. These results seem to show that a folic acid deficiency lowers a preventive power from the infection with Salmonella enteritidis in digestive tracts.
日本ビタミン学会の論文