シロネズミの葉酸欠乏食飼育について

概要

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Rats were fed for long time on a folic acid deficient diet which was modified from the Ling's deficient diet. The obtained results were as follows : (1) Increase in weight of the rats fed the folic acid deficient diet was remarkably delayed as compared with that of control (fed the pteroylglutamic acid contained diet). (2) The contents of folic acid and citrovorum factor in blood and liver of the rats reared on the folic acid deficient diet were measured by the microbiological assay. Both of them began to decrease after 40-50 days feeding. In 90 day feeding the decrease of them became remarkable and especially, the contents of folic acid and citrovorum factor in liver showed a more marked decrease than those in blood.
日本ビタミン学会の論文