肝障害時におけるパントテン酸代謝 : (I)健常人ならびに肝疾患々者の尿パントテン酸排泄量について

概要

論文の詳細を見る
The urinary content of pantothenic acid (PaA) was measured using Lactobacillus arabinosus 17-5. The microbiological assay for PaA was essentially similar to that of Skeggs. The urinary content of PaA of patients with various liver diseases was less than that of normal subjects. The increase of urinary PaA following an intramuscular adminstration of 20mg Ca-PaA was also less marked in patients with liver diseases, but the increase was more marked in patients with severe hepatic damage in comparison with that of normal subjects. The simultaneous intravenous infusion of 20 ml of 40% glucose solution caused a definite decrease in urinary PaA following the administration of 20 mg Ca-PaA in normal adults, but slight increase in most patients with liver disease.
日本ビタミン学会の論文