ビタミンB_1大量投与にかんする臨床的ならびに実験的研究 : (III)ビタミンB_1誘導体とその大量療法

概要

論文の詳細を見る
Thiamine contents in the organs of the normal rats after an administration of thiamine derivatives, such as TPD, TTFD, CAT, were examined. In blood, liver and kidney, total thiamine and cocarboxylase contents increased remarkably by the injection of TPD, TTFD or CAT as compared with the injection of thiamine hydrochloride. In the case of oral administration, urinary thiamine excretion by the administration of TPD, TTFD, CAT showed an extremely high value than that by thiamine hydrochloride administration. Clinical effect of thiamine derivatives was remarkable, especially for beri-beri and neuritis. These thiamine derivatives have a superiority over thiamine hydrochloride on affinity to the tissues and maintenance of high thiamine value of tissues.
日本ビタミン学会の論文
1966-02-25