ビタミンB_6の腹水腫瘍細胞へのとりこみ : (III)ビタミンB_6のとりこみと細胞内代謝との関連

概要

論文の詳細を見る
It was clarified in the previous report that pyridoxal and pyridoxal phosphate were uptaken by the ascites-sarcoma cells and these uptake processes depended upon temperature, properties of incubation medium, and energy supply. In order to clarify the relationship between the uptake of these vitamins and intracellular metabolism, intracellular lactate, phosphate, and ATP were determined under the conditions of uptake of these vitamins. Intracellular lactate and ATP corresponded almost in parallel with the uptaken amount of the vitamins. Pyridoxal phosphokinase activity was found in the soluble fraction of homogenate of the cells but not in the membrane fraction. The enzyme activity was inhibited moderately by 4-deoxypyridoxine.
日本ビタミン学会の論文
1970-10-25