繊維物質の加水分解と其の醗酵に関する研究 (第10報) : 加水分解物のペニシリン醗酵 : (i) ペントーズのペニシリン醗酵

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It was proved that pure d-xylose and 1-arabinose are easily assimilated by Penicillium chrysogenum as the C-source giving considerable amount of Penicillin as a metabolic product. Pentoses from natural resources (rice hulls) and wood sugar were also metabolized to produce Penicillin. But the germination and growth of the fungus were delayed as compared with lactose or glucose medium, and the best yield was obtained when used with the addition of 0.5% CaCO_3 and 0.05% NaHSO_3 to the medium.Medium and culture results : Corn steep liquor 4.0 vol%, NaNO_3 0.3%, KH_2PO_4 0.25%, MgSO_4 0.05%, ZnSO_4 0.003%, and phenyl acetic acid was added at intervals of 24hrs.After 48hrs culture. 1-arabinose 4% 1196u/cc (after 168hrs) d-xylose 4% 580u/cc (after 168hrs) pentose from rice hulls 3% 830u/cc(after 168hrs) wood sugar 3% 599u/cc (after 120hrs) pentose 3% + 0.5% CaCO_3 + 0.05% NaHsO_8 880 u/cc (after 144hrs)
社団法人日本生物工学会の論文
1950-12-15