Guanosine-3′, 5′-cyclic monophosphate (Cyclic GMP) Stimulates Ciliary Motility in Rabbit Cultured Tracheal Epithelium

スポンサーリンク

概要

• 論文の詳細を見る

• To determine the effect of guanosine-3′, 5′-cyclic monophosphate (cGMP) on airway epithelial function, we measured ciliary beat frequency (CBF) of cultured rabbit tracheal epithelium in response to dibutyryl cGMP. Addition of dibutyryl cGMP increased CBF in a dose-dependent fashion, an effect that was not accompanied by alteration in intracellular adenosine-3′, 5′-cyclic monophosphate (cAMP) levels. These findings suggest that cGMP, one of the important second messengers, may directly stimulate respiratory ciliary motility, and thus regulate mucociliary transport function in the airway.

• 日本呼吸器内視鏡学会の論文
• 1991-01-25

著者

• Chiyotani Atsushi

  First Department Of Medicine Tokyo Women's Medical College

• Kobayashi Kenji

  First Department of Medicine, Tokyo Women's Medical College

• Tamaoki Jun

  First Department Of Medicine Tokyo Women's Medical College

• Kobayashi Kenji

  First Department Of Medicine Tokyo Women's Medical College

• Tamaoki Jun

  Hiroshima University

関連論文

• Lower urinary tract symptoms and risk of prostate cancer in Japanese men
• Elimination of IL-13 Reverses Established Goblet Cell Metaplasia into Ciliated Epithelia in Airway Epithelial Cell Culture
• Hypotonicity-Induced ATP Release Is Potentiated by Intracellular Ca^ and Cyclic AMP in Cultured Human Bronchial Cells
• Guanosine-3′, 5′-cyclic monophosphate (Cyclic GMP) Stimulates Ciliary Motility in Rabbit Cultured Tracheal Epithelium
• Effect of Clarithromycin on Transepithelial Potential Difference in Rabbit Tracheal Mucosa
• Effect of Saiboku-to, an Antiasthmatic Herbal Medicine, on Nitric Oxide Generation from Cultured Canine Airway Epithelial Cells
• The Role of a Self-management Program in the Control of Mild to Moderate Asthma : a Randomized Controlled Study
• Mechanisms of Airway Remodeling in Asthma
• Advancements in Urology 2011 : A Japanese Urological Association (JUA)/American Urological Association (AUA) Symposium
• Role of a Th2 cytokine inhibitor in asthma treatment
• Potentiation of .BETA.-Adrenergic Function by Saiboku-To and Bakumondo-To in Canine Bronchial Smooth Muscle.

もっと見る 閉じる

スポンサーリンク