<Originals>Plasma Sulpho-conjugated Catecholamine Responses to Moderate Steady-state Exercise

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概要

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• OGAKI, T., SAITO, A., HOTTA, N., UEDA, N., KANAYA, S. and FUJINO, T., Plasma Sulpho-conjigated Catecholamine Responses to Moderate Steady-state Exercise. Adv. Exerc. Sports Physiol., Vol.7, No.3 pp.87-92, 2001. The purpose of this study was to investigate the time course of the plasma sulpho-conjugated catecholamines (CA) during moderate steady-state exercise. Six male university runners exercised at 70% of maximal oxygen uptake for 60 min on a cycle ergometer. The plasma free and sulfated CA were measured before exercise, every 10 min during exercise and at 30 min and 60 min after exercise. The concentrations of plasma free noradrenaline (NA), adrenaline (AD) and dopamine (DA) compared with the pre-exercise levels were elevated significantly at 10 min (p<0.01). 50 min (p<0.01) and 20 min (p<0.05), respectively. The plasma NA sulfate (NA-S) and AD sulfate (AD-S) concentrations increased gradually with exercise duration and weresignificantly elevatedover pre-exercise values at 20 min (p<0.01) and 30 min (p<0.05), resoectively. The plasma DA sulfate (DA-) concentration showed a transitory decrease after 10 min and 20 min of exercise (p<0.05) and then increased gradually with exercise and reached a statisically significant level by the end of exercise (p<0.001). All three sulfated CA concentrations remained elevated for 60 min after exercise (p<0.01 - P<0.001). The ratio of free AD and NA to total (free - conjugated ) AD and NA concentrations reached steady-state levels after 20 min of exercise. We conclude that the concentrations of all three CA sulfates increase during exercise when plasma free CA conentrations reached sufficient levels. In addition, our results suggest that the plasma free CA, especially free AD and NA released during exercise may undergo sulphoconjugation during exercise as well as after exercise. Moreover, we noted that the plasma DA-S concentration decreased temporarily during an early stage of exercise, although the mechanism remains unclear.

• 日本運動生理学会の論文

著者

• Hotta Noboru

  Institute of Health Science, Kyushu University

• Hotta Noboru

  Institute Of Health Science Kyushu University

• Hotta Noboru

  Inst. Of Health Sci. Kyushu Univ.

• OGAKI Tetsuro

  Institute of Health Science, Kyushu University

• Saito Atsushi

  Institute of Health Science,Kyushu University

• Ogaki Tetsuro

  Institute Of Health Dcience And Graduate School Of Human Environmental Studies Kyushu University

• Saito Atsushi

  Institute For Materials Research Tohoku University

• OGAKI Tetsuro

  Kyushu Univ.

• Saito Atsushi

  Institute Of Health Science Kyushu University

• Ogaki Tetsuo

  Institute of Health Science,Kyushu University

• Ogaki Tetsuo

  Institute of Health Science, Kyushu University

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