Blood Coagulation and Fibrinolysis of Rats Fed Fish Oil : Reduced Coagulation Factors Especially Involved in Intrinsic Pathway and Increased Activity of Plasminogen Activator Inhibitor(Food & Nutrition Science)

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概要

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• Differences in the coagulation and fibrinolytic system of rats fed a fish oil based diet (fish oil diet) and fed a soybean oil based diet (control diet) were determined. Concentrations of plasma lipids were depressed in rats fed the fish oil diet. Prothrombin time (PT) and activated partial thromboplastin time (APTT) of rats fed the fish oil diet were longer than for the rats fed the control diet. Fish oil intake lowered the activities of most of the blood coagulation factors, and strongly depressed the factors involved in the intrinsic pathway. Fish oil also affected the fibrinolysis of rats. Plasminogen activator inhibitor (PAI) activity was elevated in rats fed the fish oil diet. In this study, both blood coagulation and fibrinolysis were down-regulated by feeding the fish oil diet.

• 社団法人日本農芸化学会の論文
• 2003-10-23

著者

• Murata Masakazu

  Laboratory Of Applied Microorganisms Marine Biochemistry Division National Research Institute Of Fis

• Sato K

  Okayama Univ. Okayama Jpn

• Sato Kaori

  Laboratory Of Applied Microorganisms Marine Biochemistry Division National Research Institute Of Fis

• Uchida Motoharu

  Laboratory Of Applied Microorganisms Marine Biochemistry Division National Research Institute Of Fis

• SANO Yoko

  Laboratory of Applied Microorganisms, Marine Biochemistry Division, National Research Institute of F

• Sano Yoko

  Laboratory Of Applied Microorganisms Marine Biochemistry Division National Research Institute Of Fis

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• Fundamental Study of Latent Cold Heat Energy Storage by Means of Oil Droplets at Low Freezing Poing : Numerical Calculation of Motion and Solidification Characteristics of Oil Droplets Ascending in a Cold Water Solution due to Buoyancy
• Alteration by Diacylglycerols of the Transport and Fatty Acid Composition of Lymph Chylomicrons in Rats
• Blood Coagulation and Fibrinolysis of Rats Fed Fish Oil : Reduced Coagulation Factors Especially Involved in Intrinsic Pathway and Increased Activity of Plasminogen Activator Inhibitor(Food & Nutrition Science)
• Measurements of Cavitation Inception
• Triacylglycerol and Fatty Acid Synthesis in Hepatocytes in Suspension Isolated from Rats Fed Soybean Phospholipid

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