Active and Passive Exposure Status to Tobacco Smoke of Department Store Employees Measured by Cotinine ELISA
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概要
- 論文の詳細を見る
Quantitation of urinary cotinine, a major metabolite of nicotine, by an enzyme-linked immunosorbent assay (ELISA), was performed in parallel with questionnaires containing items on smoking status, such as active and/or passive smokers, the number of cigarettes smoked, and the presence or absence of active smokers in the surroundings in a department store (517 employees). The cotinine values corrected by creatinine (cotinine-creatinine ratios, CCRs) approximately conformed to the extent of self-recognition of their exposure status to tobaccosmoke, and were low in the order of active smokers, passive smokers and non-smokers who felt they were not exposed to tobacco-smoke. Occupational differences of the CCRs were not found in the employees. In the active smokers, the CCRs were increasing according to the number of cigarettes per day they smoked, and the values were nearly proportional to nicotine contents of cigarette in the moderate smokers who smoked 11-20 cigarettes per day. The CCRs of males were higher than those of females in the active smokers, which also agreed well with the numbers of cigarettes they smoked per day. In the passive smokers, the CCRs were remarkably and significantly higher in subjects who felt they were exposed to tobacco-smoke both in their workplaces and homes. Urinary CCRs measured by ELISA are thus found to be a reliable and excellent objective indicator of both active and passive exposure-status to tobacco-smoke.
- 日本衛生学会の論文
著者
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Zheng Yan
Department of Medical Microbiology, Shandong University School of Medicine
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DOHI YOSHIKO
Department of Public Health, Health Management and Policy, Nara Medical University
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Dohi Yoshiko
Department Of Public Health Nara Medical University
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Dohi Yoshiko
Department Of Public Health Health Management And Policy Nara Medical University
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Zheng Yan
Department Of Public Health Nara Medical University
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Zheng Yan
Department Of Applied Chemistry School Of Chemical And Material Engineering Southern Yangtze Univers
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Mizutani Rika
Department Of Public Health Nara Medical University
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Yoshioka Nobuo
Department Of Public Health Nara Medical University
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KURUMATANI Norio
Department of Public Health, Nara Medical University
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SAKANASHI Teruko
Department of Public Health Nara Medical University
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YONEMASU Kunio
Department of Public Health Nara Medical University
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Yonemasu K
Nara Medical Univ. Nara Jpn
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OHKADO Takashi
Department of Public Health, Nara Medical University
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Ohkado Takashi
Department Of Public Health Nara Medical University
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Kurumatani N
Nara Medical Univ. Nara Jpn
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Kurumatani Norio
Department Of Hygiene Nara Medical University
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Kurumatani Norio
Department Of Community Health And Epidemiology Nara Medical University School Of Medicine
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