Nuclear Localization of Senescence Marker Protein-30, SMP30, in Cultured Mouse Hepatocytes and Its Similarity to RNA Polymerase(Biochemistry & Molecular Biology)

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概要

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• Senescence marker protein-30 (SMP30), expressed mostly in the liver, protects cells against various injuries by stimulating membrane calcium-pump activity. By immunohistochemistry and western blotting, we found that SMP30 was in both the nuclei and cytoplasm of cultured mouse hepatocytes. By a homology search, we found that a domain of the SMP30 sequence 51 amino acid residues long was 60-66% similar to bacterial and yeast RNA polymerases.

• 社団法人日本農芸化学会の論文
• 2003-01-23

著者

• Ishigami Akihito

  Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho University

• Maruyama Naoki

  Tokyo Metropolitan Institute Of Gerontology Keio University

• MARUYAMA Naoki

  Department of Molecular Pathology, Tokyo Metropolitan Institute of Gerontology

• Maruyama N

  Energy System Design Laboratory Department Of Mechanical Engineering Mie University

• Maruyama N

  Tokyo Noko Univ. Tokyo Jpn

• Ishigami Akihito

  Dep. Of Biochemistry Fac. Of Pharmaceutical Sciences Toho Univ.

• Maruyama Nobuyuki

  Tokyo Metropolitan Institute Of Gerontology

• HANDA Setsuko

  Department of Molecular Pathology, Tokyo Metropolitan Institute of Gerontology

• SUPAKAR Prakash

  Institute of Life Sciences, Nalco Square

• Ishigami Akihito

  Department Of Biochemistry Faculty Of Pharmaceutical Science Toho University

• Handa Setsuko

  Department Of Molecular Pathology Tokyo Metropolitan Institute Of Gerontology

• Supakar Prakash

  Institute Of Life Sciences Nalco Square

• Maruyama Naoki

  Department Of Molecular Pathology Tokyo Metropolitan Institute Of Gerontology

• Maruyama Naoki

  Department Of Autonomic Neuroscience Tokyo Metropolitan Institute Of Gerontology

• Handa Setsuko

  Tokyo Metropolitan Inst. Gerontology Tokyo Jpn

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