Oxidation of Two Pregnane Steroids Catalyzed by the Fungus Cephalosporium aphidicola
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概要
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Two pregnane steroids, pregnane (1) and 3β-hydroxypregnane (2), were oxidized by fermentation with the fungus Cephalosporium aphidicola. The fermentation of pregnane (1) yielded 3β-hydroxypregnane (2) and 3β, 6β, 11α-trihydroxypregnane (3), while that of 3β-hydroxypregnane (2) afforded 6β, 11α-dihydroxypregn-3,20-dione (4), 3β, 6β, 15α-trihydroxypregn-20-one (5) and 3β, 5α, 11α-trihydroxypregn-20-one (6). The metabolites are characterized by detailed physical and spectroscopic studies.
- 社団法人日本農芸化学会の論文
- 1999-10-23
著者
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Hanson J.r.
School Of Molecular Sciences University Of Sussex Falmer
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FAROOQ Afgan
School of Molecular Sciences, University of Sussex, Falmer
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Farooq Afgan
School Of Molecular Sciences University Of Sussex Falmer