Alkaloid Production during the Cultivation with Shaking of Claviceps sp. : Effects of Asparagine

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概要

• 論文の詳細を見る

• Among the nitrogen sources tested, asparagine stimulated alkaloid production maximally. Ammonium salts supported alkaloid production poorly. During the cultivation with shaking of Claviceps sp. strain SD-58 in asparagine containing medium, the activity of asparaginase increased during the exponential growth (up to 8 days) with the intracellular accumulation of ammonium ions. Among the ammonia-assimilating enzymes we studied, NADP^+-glutamate dehydrogenase (GDH) had a higher activity in the growth phase (up to 6 days), while in the intensive alkaloid producing phase (after 6 days) the activity of glutamine synthetase was higher. The latter was associated with increases in the intracellular level of tryptophan and alkaloid production. The levels of NADP^+- and NAD^+-alanine dehydrogenases and glutamate synthase were negligible.

• 社団法人日本生物工学会の論文
• 1986-08-25

著者

• Desai J

  Indian Petrochemicals Corporation Ltd. Gujarat Ind

• Desai A

  (present Address)department Of Microbiology M.s. University Of Baroda

• Desai J.d.

  (present Address)applied Biology Division Research Centre Indian Pertochemicals Corporation Limited

• PATEL H.C.

  Department of Bioscience, Sardar Patel University

• DESAI J.D.

  Applied Biology Division, Research Centre, Indian Petrochemicals Corporation Limited

• DESAI A.J.

  Department of Microbiology, Faculty of Science, M.S. University of Baroda

• Patel H.c.

  Department Of Bioscience Sardar Patel University

関連論文

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• Effect of Tween Series Surfactants on Alkaloid Production by Submerged Cultures of Claviceps Species
• Alkaloid Production during the Cultivation with Shaking of Claviceps sp. : Effects of Asparagine

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