Application of an Optimization Algorithm for Estimating Intrinsic Kinetic Parameters of Immobilized Enzymes(BIOCHEMICAL ENGINEERING)
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概要
- 論文の詳細を見る
A simple optimization methodology is applied to estimate the intrinsic kinetic parameters for both reversible and irreversible unireactant immobilized enzyme systems that follow the Michaelis-Menten mechanism. The method utilizes a direct-search optimization algorithm along with the numerical solution of the governing differential equations. The usefulness and validity of the method is demonstrated by comparing the predicted values of the intrinsic kinetic constants using the proposed method with a series of experimental values reported in the literature for different immobilized enzyme systems with irreversible and reversible reactions.
- 公益社団法人日本生物工学会の論文
- 2002-07-25
著者
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Kheirolomoom Azadeh
Department Of Chemical Engineering Kyoto University
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Kheirolomoom Azadeh
Department Of Chemical Engineering Sharif University Of Technology
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KHORASHEH FARHAD
Department of Chemical Engineering, Sharif University of Technology
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MIRESHGHI SEYEDALIREZA
Biotechnology Group, Science and Research Campus, Islamic Azad University
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Mireshghi Seyedalireza
Biotechnology Group Science And Research Campus Islamic Azad University
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Khorasheh F
Department Of Chemical Engineering Sharif University Of Technology
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- Application of an Optimization Algorithm for Estimating Intrinsic Kinetic Parameters of Immobilized Enzymes(BIOCHEMICAL ENGINEERING)