α-Amylase Production in Recombinant Aspergillus oryzae during Fed-Batch and Continuous Cultivations
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概要
- 論文の詳細を見る
Three α-amylase producing strains of Aspergillus oryzae used for recombinant protein production have been studied with respect to growth and protein production in fed-batch and continuous cultures. The three strains are(i)a wild-type, (ii)a transformant strain of the wild-type strain containing additional copies of the α-amylase gene and(iii)a morphological mutant of the transformant strain. It is found that production of α-amylase is a growth related process. Comparison of the three strains with respect to morphology and protein production reveals that changes in the morphology of the fungus influence the α-amylase production during submerged growth.
- 公益社団法人日本生物工学会の論文
- 1998-07-25
著者
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Villadsen J
Technical Univ. Denmark Lyngby Dnk
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Villadsen John
Center For Process Biotechnology Department Of Biotechnology Building 223 Technical University Of De
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Nielsen Jens
Center For Process Biotechnology Department Of Biotechnology Building 223 Technical University Of De
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Spohr Anders
Center For Process Biotechnology Department Of Biotechnology Technical University Of Denmark
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CARLSEN MORTEN
Center for Process Biotechnology, Department of Biotechnology, Technical University of Denmark
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Carlsen Morten
Center For Process Biotechnology Department Of Biotechnology Technical University Of Denmark
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