レジスタンス運動トレーニングが成長期ラットの大腿骨骨密度に及ぼす影響

概要

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The purpose of this study was to determine whether resistance exercise training alters the femur bone mineral density (BMD) of rats. Male Sprague-Dawley rats, 8 week of age, were divided into three groups : sendentany, sham-training and resistance training. After 2-wk of adaptation period, resistance training rats performed squatting at 65〜70% of one repetition maximum (1RM) for 120 repetitions / day and 3〜4 days / week for 12 weeks. 1RM was redetermined every two weeks, and the maximum loads of between 1.0 and 2.9kg were progressively increased amounts of weight applied to the wooden arm. Sham-training rats completed the same exercise protocol without applied to the weight. Wet and dry weight / body weight of femur were 15% and 10% heavier, respectively, after the resistance training than those of the sedentary group. Bone diameter of femur was significantly greater in the resistance training group compared with the sedentary and sham-training group. Femur total BMD was also significantly greater in trained rats, and the increase in BMD was most pronounced in midshaft, especially rich cortical bone.In conclusion, (1) resisntance exercise training in growing rats increased BMD in the femur, and (2) provide a suitable animal model about the study of bone adaptation to resistance exercise.
日本運動生理学会の論文
2000-01-31