Scale-Up of Interleukin-6 Production by BHK Cells Using a Radial-Flow Reactor Packed with Porous Glass Beads
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概要
- 論文の詳細を見る
A radial flow packed-bed bioreactor was developed for continuous large scale culture of mammalian cells. A 5,000 ml-bed bioreactor (RA5000) was constructed to assess the scalability of this culture system. The medium feed rate and the glucose consumption rate attained 175 l/d and 450 g/d, respectivley. The IL-6 production in a RA5000 corresponded to about 10 times that in a 400 ml-bed bioreactor (RA400).
- 社団法人日本生物工学会の論文
- 1997-09-25
著者
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Yoshida Hitoshi
Central Laboratories For Key Technology Kirin Brewery Co. Ltd.
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Yoshida Hitoshi
Central Laboratories For Key Technolog Kirin Brewery Co. Ltd.
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Ikenaga Hiroshi
Central Laboratories for Key Technology, Kirin Brewery Co., Ltd.
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Ikenaga Hiroshi
Central Laboratories For Key Technology Kirin Brewery Co. Ltd.
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MIZUTANI SATORU
Central Laboratories for Key Technology, Kirin Brewery Co. Ltd.,
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Mizutani Satoru
Central Laboratories For Frontier Technology Kirin Holdings Company Limited
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Mizutani Satoru
Central Laboratories For Key Technology Kirin Brewery Co. Ltd.
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Mizutani Satoru
Central Labo Ratories For Frontier Technology Kirin Holdings Company Ltd.
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Ikenaga Hiroshi
Central Laboratories for Key Technology, Kirin Brewery Co. Ltd.,
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