Stereoselective Syntheses of (-)-Podorhizol Lignan and its Derivatives : erythro and threo Preferential Aldol Condensation of Potassium Enolate from γ-Butyrolactone with Alkoxybenzaldehyde
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概要
- 論文の詳細を見る
(-)-Podorhizol (1) was stereoselectively synthesized by erythro preferential aldol condensation of 3,4,5-trimethoxy-benzaldehyde with potassium enolate from (+)-(R)-3-(3,4-methylenedioxybenzyl)-4-butanolide (2) (erythro : threo=85.15). Erythro selectivity was observed in the aldol condensation of many alkoxybenzaldehydes with potassium enolate from (+)-γ-butyrolactone 2. However, benzaldehydes having methoxy groups at both the 2 and 6 positions gave threo selectivity in the aldol condensation with potassium enolate from (+)-γ-butyrolactone 2.
- 社団法人日本農芸化学会の論文
- 1999-08-23
著者
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YAMAUCHI Satoshi
College of Agriculture, Ehime University
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Kinoshita Yoshiro
College Of Agriculture Ehime University
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MACHI Mitsuo
College of Agriculture, Ehime University
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Machi Mitsuo
College Of Agriculture Ehime University
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Yamauchi Satoshi
College Of Agriculture Ehime University
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Kinoshita Yoshiro
College Of Agricullture Ehime University
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Yamauchi Satoshi
College Of Agricullture Ehime University
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