Suppression of Interleukin-2 Receptor Expression on Mouse CD4^+ T Cells by Bovine κ-Caseinoglycopeptide

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概要

• 論文の詳細を見る

• Bovine κ-caseinoglycopeptide (residues 106-169, CGP) completely inhibited the PHA-induced proliferation of mouse splenocytes when CGP was added simultaneously with PHA. The inhibitory effect, however, was reduced to about one-half when CGP was added after 24h of cultivating the splenocytes with PHA or when anti-IL-1ra antibody was added simultaneously with PHA and CGP. On the other hand, CGP bound to mouse CD4^+ T cells but not to CD8^+ T cells. CGP suppressed IL-2 receptor expression of the PHA-stimulated mouse CD4^+ T cells.

• 社団法人日本農芸化学会の論文
• 1996-06-23

著者

• Otani Hajime

  Division of Animal Science, Faculty of Agriculture, Shinshu University

• Monnai Makoto

  The United Graduate School Of Agricultural Science Gifu University

• HORIMOTO Yasuhiro

  Division of Animal Science, Faculty of Agriculture, Shinshu University

• Horimoto Yasuhiro

  Division Of Animal Science Faculty Of Agriculture Shinshu University

• Otani Hajime

  Division Of Animal Science Faculty Of Agriculture Shinshu University

関連論文

• Induction of an Interleukin-1 Receptor Antagonist-like Component Produced from Mouse Spleen Cells by Bovine K-Caseinoglycopeptide
• Suppression of Interleukin-2 Receptor Expression on Mouse CD4^+ T Cells by Bovine κ-Caseinoglycopeptide

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