Inverse Relationship between Homoserine Dehydrogenase Activity and Uridine Productivity in a Pyrimidine Analogue-resistant Mutant of Bacillus subtilis

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概要

• 論文の詳細を見る

• A uridine-overproducing mutant of Bacillus subtilis was found to require homoserine for growth due to a defect of homoserine dehydrogenase. When the mutant reverted back to prototropy, the production of uridine was decreased by about 40%; the decrease was, however, restored to an appreciable extent by adding aspartic acid, the common precursor for the biosynthesis of homoserine and UMP.

• 社団法人日本農芸化学会の論文
• 1996-04-23

著者

• Asahi Satoru

  Technology Development Laboratories Takeda Chemical Industries Ltd.

• Kawano Akira

  Technology Development Laboratories Takeda Chemical Industries Ltd.

• Doi Muneharu

  Technology Development Laboratories Takeda Chemical Industries Ltd.

関連論文

• Opimization of Conditions for Production of Uridine by a Mutant of Bacillus subtilis
• Inverse Relationship between Homoserine Dehydrogenase Activity and Uridine Productivity in a Pyrimidine Analogue-resistant Mutant of Bacillus subtilis

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