Syntheses of (14β,15β,16β,17α)- and (14β,15α,16β,17α)-1,3,5(10)-Estratriene-2,3,14,15,16,17-hexaols, Possible Candidates for the Inagami-Tamura Endogenous Digitalis-like Factor, and Their Activity

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概要

• 論文の詳細を見る

• Structures are proposed for the Inagami-Tamura endogenous digitalis-like factor (EDLF), and two possible candidates, (14β,15β,16β,17α)- and (14β,15α,16α,17α)-2,3,14,15,16,17-hexahydroxy-1,3,5(10)-estratrienes, were synthesized. Both compounds were potent in inducing a contractile response in isolated rat aorta and guinea pig left atrium.

• 社団法人日本農芸化学会の論文
• 1996-03-23

著者

• Sakakibara M

  Pharmaceutical Research Laboratories Kirin Brewery Co. Ltd.

• Sakakibara Masayuki

  Pharmaceutical Lab. Kirin Brewery Co. Ltd.

• OGAWA UCHIDA

  Pharmaceutical Research Laboratories, Kirin Brewery Co., Ltd.

• Ogawa Uchida

  Pharmaceutical Research Laboratories Kirin Brewery Co. Ltd.

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