Synthesis and Fungicidal Activities of 4H,6H-Furo[3,4-c]isoxazole Derivatives as Potential New Fungicides

概要

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Furoisoxazoles IIa-r, bicyclic isoxazoles, were designed and synthesized as potential new plant fungicides. The fungicidal activity of each appeared over a broad spectrum of plant pathogens. The preliminary structure-activity relationship for furoisoxazoles II suggests that the methyl and chlorophenyl groups at the 3- and 6-positions, respectively, are essential to their high fungicidal activity. In particular, isoxazoles IIb and IId showed 50% control of RCB and CGM, respectively, at 10ppm.
社団法人日本農芸化学会の論文
1994-06-23