Effects of Cultural Conditions on CDP-choline Production by Hydrocarbon Assimilating Yeasts : Enzymatic Studies on Nucleic Acid Related Compounds of Microorganisms (IV)

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A CDP-choline-producing yeast, the strain N-25-2,which was isolated in our laboratory as a hydrocarbon-assimilating yeast was classified in the genus Candida.This strain gave a high yield of cells from hydrocarbons and other carbon sources, and accumulated a large amount of lipid in the cells.To compare this strain with other yeasts, the CDP-choline productivity by lyophilized cells of several yeasts was tested. Other hydrocarbon-assimilating yeasts of the genera Torulopsis and Brettanomyces showed comparably high productivities of CDP-choline to Candida sp. N-25-2. Some Saccharomyces yeasts also showed a high productivity.Favorable cultural conditions were sought for the preparation of yeast cells capable of producing CDP-choline. The CDP-choline productivity of Candida sp. N-25-2 was found to be affected by aeration and carbon sources in the culture medium.
公益社団法人日本生物工学会の論文
1981-06-25