Coronary Spastic Angina in Patients With Connective Tissue Disease
スポンサーリンク
概要
- 論文の詳細を見る
Background Connective tissue disease, which is an inflammatory condition represented by C-reactive protein (CRP), is a risk factor for ischemic heart disease. The aim of the present study was to examine if there is a relationship between connective tissue disease and coronary spastic angina, and whether the inflammatory condition was associated with ischemic heart disease, even in patients with connective tissue disease. Methods and Results The study group comprised 73 consecutive patients with connective tissue disease who were admitted to the Department of Cardiovascular Medicine between April 2000 and March 2003. Of the 73 patients, 38 (19 men, 19 women) were diagnosed as having an ischemic heart disease (7 patients acute coronary syndrome, 19 patients coronary spastic angina, 12 patients stable exertional angina). In the present study, 19 (50.0%) of the 38 patients of ischemic heart disease were diagnosed as having coronary spastic angina. In the same study period, 151 (38.7%) of 390 patients with ischemic heart disease (without connective tissue disease) were diagnosed as having coronary spastic angina. The frequency of the patients with coronary spastic angina tended to be higher in patients with connective tissue disease than in patients without connective tissue disease. Among the study patients, serum CRP concentrations (mg/dl) were higher in patients with acute coronary syndrome (1.50±1.19, n=7) and those with coronary spastic angina (1.06±1.78, n=19) than in those with nonischemia (0.35±0.40, n=35, p<0.05). Conclusions Coronary spastic angina is a frequent complication in patients with connective tissue disease and the inflammatory condition is associated with coronary spastic angina and unstable angina in patients with connective tissue disease.
- 社団法人日本循環器学会の論文
- 2004-03-20
著者
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Tanaka Tomoko
Department of Life and Environment Engineering, The University of Kitakyushu
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Ogawa Hisao
Department of Cardiology, Kumamoto University
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Yoshimura Michihiro
Department of Caldiology Jikei University School of Medisine
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Kojima Sunao
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Sakamoto Tomohiro
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Hokamaki Jun
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Sugiyama Seigo
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Soejima Hirofumi
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Hirobe K.azuhiko
Department Of Cardiovascular Med. Kumamoto Univ.
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Kawano Hiroaki
Department of Cardiovascular Medicine, Kumamoto University
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Kishikawa Hideki
Health Care Center, Kumamoto University
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Sugiyama Seigo
Department Of Cardiovascular Medicine Graduate School Of Medical Science Kumamoto University
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Kojima Sunao
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto Uinversity
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MIYAMOTO Shinzo
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Kuriyama Hiroshi
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Miyamoto Shinzo
Division Of Cardiology Kumamoto Central Hospital
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Hokamaki Jun
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Tanaka Tomoko
Department Of Cardiovascular Medicine National Hospital Organization Kumamoto Medical Center
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Satoh Toru
Division Of Cardiology Saiseikai Kumamoto Hospital Cardiovascular Center
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Hokamaki Jun
Department Of Cardiology Japanese Red Cross Kumamoto Hospital
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Soejima Hirofumi
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Soejima Hirofumi
Department Of Cardiology Kumamoto Chuo Hospital
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Miyamoto Shinzo
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Ogawa Hisao
Department Cardiovascular Medicine Kumamoto University:division Of Intensive Care Unit Kumamoto Univ
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Kawano Hiroaki
Department Cardiovascular Medicine Kumamoto University:division Of Intensive Care Unit Kumamoto Univ
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Hokamaki Jun
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences
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Kurihara Hiroki
Department Of Physiological Chemistry And Metabolism Graduate School Of Medicine University Of Tokyo
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Sakamoto Mieko
Division Of Cardiology Kumamoto Central Hospital
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Soejima Hirofumi
Department Of Cardiovascular Medicine Graduate School Of Medical Science Kumamoto University
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SAKAMOTO Tomohiro
Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University
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Sakamoto Tomohiro
Department of Cardiology, Saiseikai Kumamoto Hospital, Japan
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