Evaluation of Myocardial Infarction by Radioisotope Myocardial Imaging with Special Reference on Thallium-201 Myocardial Perfusion Imaging : The Present Status of Cordiovascular Nuclear Medicine
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概要
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One hundred and three patients with myocardial infarctions were studied with 201-thallium chloride and/or 99m-technetium pyrophosphate myocardial imaging and were followed-up for an average of 23 months. There were 14 false negative cases with 201-thallium chloride, but no deaths or serious complications occurred during the follow-up period in these false negative cases. There were six patients with widened QRS complexes (more than 0.12 seconds) without bundle branch blocks and in three of them myocardial infarction was not identified by electrocardiography. However, there were large myocardial perfusion defects in the anterior-inferior wall of the left ventricle. All of this group of patients died suddenly during the followup period. The incidence of complications and mortality rose sharply in patients whose myocardial perfusion defects detected by thallium-201 were larger than 40% of the entire left ventricle. The myocardial infarction areas measured by 99m-technetium pyrophosphate were 28.5 ± 9.8 cm^2 in nonsurvivors and 16.5 ± 1.7 cm^2 in survivors. In addition, ten patients with acute myocardial infarction were studied by double scan methods with thallium-201 ; myocardial perfusion defect areas were reduced from 29 ± 3% of the entire left ventricle to 19 ± 4% by nitrate administration, indicating that there were reversibly ischemic areas in acute myocardial infarction which could be transiently reduced by nitrate. Thus, the study suggests the possibility of decreasing myocardial perfusion defects in the early phase of acute myocardial infarction, leading to a better long term prognosis for the patients.
- 社団法人日本循環器学会の論文
- 1981-01-20
著者
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Suzuki Yutaka
Department Of Internal Medicine Tokai University School Of Medicine
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Tomoda Haruo
Department Of Cardiology
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Tomoda Haruo
Department Of Cardiology And Radiology School Of Medicine Tokyo University
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Suzuki Yutaka
Department Of Cardiology And Radiology School Of Medicine Tokyo University
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SUZUKI Yutaka
Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University
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